Our One Health training focuses on developing competence for the application of molecular biology and analytical epidemiology to understand and manage risk associated with infectious diseases through a tiered postgraduate programme.

We aim to develop  world-class research students and fellows, addressing capacity gaps and the convergent need in science and technology that make linking medical and veterinary research efficient and effective in the resource poor settings of sub Saharan  Africa

Antimicrobial Resistance Profiles, Virulence Genes, and Genetic Diversity of Thermophilic Campylobacter Species Isolated From a Layer Poultry Farm in Korea

yunus.karsan@sacids.org
Authors: Noel Gahamanyi, Dae-Geun Song, Kye-Yoon Yoon, Leonard E. G. Mboera, Mecky I. Matee, Dieudonné Mutangana, Raghavendra G. Amachawadi, Erick V. G. Komba and Cheol-Ho Pan Abstract Thermophilic Campylobacter species are among the major etiologies of bacterial enteritis globally. This study aimed at assessing the antimicrobial resistance (AMR) profiles, virulence genes, and genetic diversity of thermophilic Campylobacter species isolated from a layer poultry farm in South Korea. One hundred…

Genomic Characterization of Fluoroquinolone-Resistant Thermophilic Campylobacter Strains Isolated from Layer Chicken Feces in Gangneung, South Korea by Whole-Genome Sequencing

yunus.karsan@sacids.org
Authors: Noel Gahamanyi, Dae-Geun Song, Kye-Yoon Yoon, Leonard E. G. Mboera, Mecky I. Matee, Dieudonné Mutangana, Erick V. G. Komba, Cheol-Ho Pan and Raghavendra G. Amachawadi   Abstract Thermophilic Campylobacter species of poultry origin have been associated with up to 80% of human campylobacteriosis cases. Layer chickens have received less attention as possible reservoirs of Campylobacter species. Initially, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of two…

Ethnobotany, Ethnopharmacology, and Phytochemistry of Medicinal Plants Used for Treating Human Diarrheal Cases in Rwanda: A Review

yunus.karsan@sacids.org
Authors: Noel Gahamanyi, Emmanuel Munyaneza, Emmanuel Dukuzimana, Naasson Tuyiringire, Cheol-Ho Pan and Erick V. G. Komba  Abstract Diarrhea, often caused by microorganisms, has been associated with high morbidity and mortality in Africa. Increased rates of antimicrobial-resistant pathogens have reignited the quest for alternative therapies. This review aimed at identifying medicinal plants used in the treatment of human diarrheal cases in Rwanda and…

Complete Genome Sequencing of Field Isolates of Peste des Petits Ruminants Virus from Tanzania Revealed a High Nucleotide Identity with Lineage III PPR Viruses

yunus.karsan@sacids.org
Authors: Edson Kinimi, Mana Mahapatra, Tebogo Kgotlele, Mariam R. Makange, Chandana Tennakoon, Felix Njeumi, Steven Odongo, Serge Muyldermans, Richard Kock, Satya Parida, Mark Rweyemamu and Gerald Misinzo Simple Summary Peste des petits ruminants virus (PPRV) causes a highly devastating disease, peste des petits ruminants (PPR), in sheep and goats, which is targeted for global control and eradication. However, in many developing countries, access to expensive sequencing…

Seroprevalence and associated risk factors of chikungunya, dengue, and Zika in eight districts in Tanzania

yunus.karsan@sacids.org
Authors: Gaspary O.Mwanyika, CalvinSindato, SimaRugarabamu, Susan F.Rumisha, Esron D.Karimuribo, GeraldMisinzo, Mark M.Rweyemamu, Muzamil M.Abdel Hamid, Najmul Haider, FrancescoVairo, Richard Kock, Leonard E.G.Mboera   Abstract Background: This study was conducted to determine the seroprevalence and risk factors of chikungunya (CHIKV), dengue (DENV), and Zika (ZIKV) viruses in Tanzania. Methods: The study covered the districts of Buhigwe, Kalambo, Kilindi, Kinondoni, Kondoa, Kyela, Mvomero, and Ukerewe in Tanzania. Blood samples were collected…

Development of Nanobodies Targeting Peste des Petits Ruminants Virus: The Prospect in Disease Diagnosis and Therapy

yunus.karsan@sacids.org
Authors: Edson Kinimi, Serge Muyldermans, Cécile Vincke, Steven Odongo, Richard Kock, Satya Parida, Mana Mahapatra and Gerald Misinzo Abstract Peste des petits ruminants virus (PPRV) causes a highly devastating disease, peste des petits ruminants (PPR) of sheep and goats, that threatens food security, small ruminant production, and the conservation of wild small ruminants in many developing countries, especially in Africa. Robust serological and…

Exposure to Salinity and Light Spectra Regulates Glucosinolates, Phenolics, and Antioxidant Capacity of Brassica carinata L. Microgreens

yunus.karsan@sacids.org
Authours:  Sylvia Maina, Da Hye Ryu, Jwa Yeong Cho, Da Seul Jung, Jai-Eok Park, Chu Won Nho, Gaymary Bakari, Gerald Misinzo, Je Hyeong Jung, Seung-Hoon Yang and Ho-Youn Kim Abstract The effect of salt treatment on Brassica carinata (BC) microgreens grown under different light wavelengths on glucosinolates (GLs) and phenolic compounds were evaluated. Quantifiable GLs were identified using ultra-high performance-quadrupole time of flight mass spectrometry.…

Genetic Analysis of African Swine Fever Virus From the 2018 Outbreak in South-Eastern Burundi

yunus.karsan@sacids.org
Authors: Jean N. Hakizimana, Lionel Nyabongo, Jean B. Ntirandekura, Clara Yona, Désiré Ntakirutimana, Olivier Kamana, Hans Nauwynck and Gerald Misinzo Abstract African swine fever (ASF) is a contagious viral disease that causes high mortality, approaching 100%, in domestic pigs and wild boars. The disease has neither a cure nor a vaccine, and it is caused by an ASF virus (ASFV), the only member of…

An assessment of the epidemiology and socio-economic impact of the 2019 African swine fever outbreak in Ngara district, western Tanzania

yunus.karsan@sacids.org
Authors: CC. Kivumbi, C.Yona, J.N. Hakizimana, G.Misinzo Abstract African swine fever (ASF) is a contagious viral transboundary animal disease affecting domestic pigs caused by ASF virus (ASFV). This study was conducted in order to determine the genetic characteristics, risk factors and socio-economic impact of an ASF outbreak in 2019 in Ngara, western Tanzania. Tissue samples from dead domestic pigs with clinical…

Complete genome analysis of African swine fever virus responsible for outbreaks in domestic pigs in 2018 in Burundi and 2019 in Malawi

yunus.karsan@sacids.org
AUTHORS: Jean N. Hakizimana, Jean B. Ntirandekura, Clara Yona, Lionel Nyabongo, Gladson Kamwendo, Julius L. C. Chulu, Désiré Ntakirutimana, Olivier Kamana, Hans Nauwynck & Gerald Misinzo    Abstract Several African swine fever (ASF) outbreaks in domestic pigs have been reported in Burundi and Malawi and whole-genome sequences of circulating outbreak viruses in these countries are limited. In the present study, complete genome sequences of ASF…
Load More