Our One Health training focuses on developing competence for the application of molecular biology and analytical epidemiology to understand and manage risk associated with infectious diseases through a tiered postgraduate programme.

We aim to develop  world-class research students and fellows, addressing capacity gaps and the convergent need in science and technology that make linking medical and veterinary research efficient and effective in the resource poor settings of sub Saharan  Africa

Two cases of chronic suppurative otitis media caused by Kerstersia gyiorum in Tanzania: is it an underappreciated pathogen in chronic otitis media?

yunus.karsan@sacids.org
Mwalutende A1, Mshana SE2, Mirambo MM3, Mushi MF2, Chalya PL1, Giliyoma JM1, Schneiderhan W4, Zimmermann O4, Groß U4 Two cases of mixed infection involving Kerstersia gyiorum causing chronic suppurative otitis media (CSOM) have been reported worldwide. We report, for the first time, two cases of CSOM due to mixed infections involving K. gyiorum in adults in Africa. Both isolates were intermediate susceptible to…

Predominance of multi-resistant gram-negative bacteria colonizing chronic lower limb ulcers (CLLUs) at Bugando Medical Center

yunus.karsan@sacids.org
Nyambura Moremi, Martha F Mushi, Mbunda Fidelis, Phillipo Chalya, Mariam Mirambo & Stephen E Mshana Infections, trauma, malignances and poorly controlled diabetes are common causes of chronic lower limb ulcerations in developing countries. Infected wound with multi-drug resistant bacteria usually are associated with increased morbidity and mortality. We report the distribution of bacteria pathogens colonizing the…

Evidence of Yersinia pestis DNA from fleas in an endemic plague area of Zambia

yunus.karsan@sacids.org
Yersinia pestis is a bacterium that causes plague which infects a variety of mammals throughout the world. The disease is usually transmitted among wild rodents through a flea vector. The sources and routes of transmission of plague are poorly researched in Africa, yet remains a concern in several sub-Saharan countries. In Zambia, the disease has been…

Urinary Tract Infections and Preeclampsia among Pregnant Women Attending Two Hospitals in Mwanza City, Tanzania: A 1:2 Matched Case-Control Study

yunus.karsan@sacids.org
Joshua Kaduma,1 Jeremiah Seni,2 Clotilda Chuma,1 Richard Kirita,3 Fridolin Mujuni,1 Martha F. Mushi,2 Frank van der Meer,4 and Stephen E. Mshana2 Urinary tract infection (UTI) and preeclampsia are common among pregnant women and are associated with adverse maternal-fetal and neonatal outcomes. Despite this, limited information exists on the association between UTIs and preeclampsia in Tanzania to guide specific management and thereby averting the adverse outcomes. A 1:2 matched case-control study (by…

Prevalence of Gastro-Intestinal Helminths in Slaughtered Cattle in Walungu Territory, South Kivu Province, Eastern Democratic Republic of Congo

yunus.karsan@sacids.org
Patrick Bisimwa Gédéon Banswe Bwihangane AHADI birindwa Wasso Shukuru An abattoir cross sectional survey was carried out to determine the prevalence of gastrointestinal parasitic helminths in slaughtered cattle at Kankinda and Mugogo Municipal abattoirs located in Walungu territory, South Kivu province, eastern Democratic Republic of Congo. Using qualitative and quantitative coprological examination, 200 fecal samples…

Predictors of the extended-spectrum-beta lactamases producing Enterobacteriaceae neonatal sepsis at a tertiary hospital, Tanzania

yunus.karsan@sacids.org
Author links open overlay panelRehemaMarandoaJeremiahSenibMariam M.MirambobLindaFalgenhauercdNyamburaMoremibMartha F.MushibNeemaKayangeaFestoManyamaaCanImirzalioglucdTrinadChakrabortycdStephen E.Mshanab   The study was conducted to establish predictors of extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE) neonatal sepsis and mortality in a tertiary hospital, Tanzania. Between July and December 2016, blood culture was performed in neonates with clinical features of sepsis and neonates/mothers/guardians were screened for ESBL colonization. Selected isolates…

Rubella Seroprevalence and real-time PCR detection of RUBV among Congolese pregnant women

yunus.karsan@sacids.org
Josue Zanga, Makola Kennedy Mbanzulu, Arnold-Freddy Kabasele, Nlandu Roger Ngatu & Dimosi Roger Wumba Rubella is an acute infectious disease caused by Rubella virus (RUBV). RUBV remains an important pathogen worldwide, causing approximately 100 000 cases of congenital rubella syndrome (CRS) every year; and the most severe consequence of rubella is teratogenicity. The aim of this study…

Mosquito-borne viruses circulating in Kinshasa, Democratic Republic of the Congo.

yunus.karsan@sacids.org
Mbanzulu KM1, Wumba R2, Mukendi JK3, Zanga JK3, Shija F4, Bobanga TL2, Aloni MN5, Misinzo G4 Diseases caused by mosquito-borne viruses are among the most important emerging diseases that threaten human and animal health, particularly in Africa. However, little attention has been paid to these diseases in the Democratic Republic of the Congo (DRC). The present cross-sectional study was undertaken between March…

Detection of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli in Market-Ready Chickens in Zambia

yunus.karsan@sacids.org
The frequent administering of antibiotics in the treatment of poultry diseases may contribute to emergence of antimicrobial-resistant strains. The objective of this study was to detect the presence of extended-spectrum β-lactamase- (ESBL-) producing Escherichia coli in poultry in Zambia. A total of 384 poultry samples were collected and analyzed for ESBL-producing Escherichia coli. The cultured E. coli isolates were subjected to…

Current Epidemiological Assessment of Bancroftian Filariasis in Tanga Region, Northeastern Tanzania.

yunus.karsan@sacids.org
Mshana HJ1, Baraka V2, Misinzo G3, Makunde WH Background. Tanzania started a countrywide lymphatic filariasis elimination programme in 2000 adopting the mass drug administration (MDA) strategy. The drug used for the programme was the combination of ivermectin and albendazole. However, there is limited information on the current epidemiological trend of the infections, where MDA implementation is ongoing. The…
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