Our One Health training focuses on developing competence for the application of molecular biology and analytical epidemiology to understand and manage risk associated with infectious diseases through a tiered postgraduate programme.

We aim to develop  world-class research students and fellows, addressing capacity gaps and the convergent need in science and technology that make linking medical and veterinary research efficient and effective in the resource poor settings of sub Saharan  Africa

Persistent domestic circulation of African swine fever virus in Tanzania, 2015–2017

yunus.karsan@sacids.org
Authors: Clara M. Yona, Merijn Vanhee, Edgar Simulundu, Mariam Makange, Hans J. Nauwynck & Gerald Misinzo Abstract Background African swine fever (ASF) is a highly fatal viral hemorrhagic disease of domestic pigs that threatens livelihoods and food security. In Africa, ASF virus (ASFV) circulates in sylvatic (transmission between warthogs and soft argasid ticks) and domestic (transmission between domestic pigs) cycles, with…

Antimicrobial use and resistance in food-producing animals and the environment: an African perspective

yunus.karsan@sacids.org
Zuhura I. Kimera, Stephen E. Mshana, Mark M. Rweyemamu, Leonard E. G. Mboera & Mecky I. N. Matee  Abstract Background The overuse of antimicrobials in food animals and the subsequent contamination of the environment have been associated with development and spread of antimicrobial resistance. This review presents information on antimicrobial use, resistance and status of surveillance systems in food animals…

Seroprevalence of human Brucellosis and associated risk factors among high risk occupations in Mbeya Region of Tanzania

yunus.karsan@sacids.org
Abstract Background Brucellosis is an infectious zoonotic disease that affects humans, livestock and wildlife. Methods A cross-sectional study was conducted in Mbeya region between November 2015 and January 2016 to investigate the seroprevalence of human brucellosis and identify associated risk factors among individuals in risky occupations in Mbeya Region. A total of 425 humans from six occupational…

Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic Review

yunus.karsan@sacids.org
Noel Gahamanyi, Leonard E. G. Mboera, Mecky I. Matee, Dieudonné Mutangana, and Erick V. G. Komba Abstract Thermophilic Campylobacter species are clinically important aetiologies of gastroenteritis in humans throughout the world. The colonization of different animal reservoirs by Campylobacter poses an important risk for humans through shedding of the pathogen in livestock waste and contamination of water sources, environment, and food. A review of…

Association of brucellosis to abortions in humans and domestic ruminants in Kagera ecosystem, Tanzania

yunus.karsan@sacids.org
Ntirandekura, J-B, Matemba, L.E.; Kimera, S.I.; Muma, J.B. and Karimuribo, E.D.  Abstract Brucellosis is a worldwide zoonotic disease of socio‐economic importance. Understanding the association of this disease with pregnancy outcome has the potential of contributing to the reduction of its reproductive burden in humans and animals among pastoral communities in Tanzania. A prospective cohort study…

Molecular characterization of Brucella species detected in humans and domestic ruminants of pastoral areas in Kagera ecosystem, Tanzania

yunus.karsan@sacids.org
Jean‐Bosco Ntirandekura, Victor A. Makene, Christopher J. Kasanga, Lucas E. Matemba, Sharadhuli I. Kimera, John B. Muma, Esron D. Karimuribo Abstract Brucellosis is a zoonotic disease of importance to both public health and the livestock industry. The disease is likely to be endemic in Tanzania and little is reported on molecular characterization of Brucella species in pastoral settings. This study aimed at characterizing Brucella species…

Molecular detection of Campylobacter species from human and cattle faecal samples in Kilosa district, Tanzania

yunus.karsan@sacids.org
Noel Gahamanyi, Leonard E.G. Mboera, Mecky I. Matee, Dieudonné Mutangana, Raghavendra G. Amachawadi, Kye-Yoon Yoon, Humphrey A. Mabwi, Kwang Hyun Cha, Cheol-Ho Pan, Erick V.G.   Abstract Background: A growing number of Campylobacter species other than C. jejuni and C. coli have been considered as emerging human and animal pathogens. However, the contribution of these species to…

Tracking characterization of Mycobacterium strains in Tanzania and some sub-Saharan African Countries: An overview on genotyping studies, implication and trends in advancing technology

yunus.karsan@sacids.org
Katale B, Keyyu J, Kendall S, Michel AL, Dockrell HM, Rweyemamu M, van Helden PD, Matee MIN.   Abstract Tuberculosis (TB) is a devastating chronic debilitating infection that imposes a considerable negative impact on human health. The disease also affects the quality of livestock, wildlife and their products. Mycobacterium tuberculosis (M. tuberculosis) is the causative…

Genetic and Biological Diversity of Porcine Sapeloviruses Prevailing in Zambia

yunus.karsan@sacids.org
Hayato Harima, Masahiro Kajihara, Edgar Simulundu, Eugene Bwalya, Yongjin Qiu, Mao Isono, Kosuke Okuya, Gabriel Gonzalez, Junya Yamagishi, Bernard M. Hang’ombe, Hirofumi Sawa, Aaron S. Mweene and Ayato Takada   Abstract Porcine sapelovirus (PSV) has been detected worldwide in pig populations. Although PSV causes various symptoms such as encephalomyelitis, diarrhea, and pneumonia in pigs, the economic impact of PSV infection remains to be determined. However, information on the…

A systematic review on integration mechanisms in human and animal health surveillance systems with a view to addressing global health security threats

yunus.karsan@sacids.org
Janeth George, Barbara Häsler, Irene Mremi, Calvin Sindato, Leonard Mboera, Mark Rweyemamu & James Mlangwa  Abstract Background Health surveillance is an important element of disease prevention, control, and management. During the past two decades, there have been several initiatives to integrate health surveillance systems using various mechanisms ranging from the integration of data sources to changing organizational structures and responses. The need…
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