Our One Health training focuses on developing competence for the application of molecular biology and analytical epidemiology to understand and manage risk associated with infectious diseases through a tiered postgraduate programme.

We aim to develop  world-class research students and fellows, addressing capacity gaps and the convergent need in science and technology that make linking medical and veterinary research efficient and effective in the resource poor settings of sub Saharan  Africa

Antimicrobial Resistance Profiles, Virulence Genes, and Genetic Diversity of Thermophilic Campylobacter Species Isolated From a Layer Poultry Farm in Korea

yunus.karsan@sacids.org
Authors: Noel Gahamanyi, Dae-Geun Song , Kye-Yoon Yoon, Leonard E. G. Mboera, Mecky I. Matee, Dieudonné Mutangana, Raghavendra G. Amachawadi, Erick V. G. Komba and Cheol-Ho Pan Abstract Thermophilic Campylobacter species are among the major etiologies of bacterial enteritis globally. This study aimed at assessing the antimicrobial resistance (AMR) profiles, virulence genes, and genetic diversity of thermophilic Campylobacter…

Susceptibility of Campylobacter Strains to Selected Natural Products and Frontline Antibiotics

yunus.karsan@sacids.org
Authors: Noel Gahamanyi, Dae-Geun Song, Kwang Hyun Cha, Kye-Yoon Yoon, Leonard E.G. Mboera, Mecky I. Matee, Dieudonné Mutangana, Raghavendra G. Amachawadi, Erick V.G. Komba and Cheol-Ho Pan   Abstract Campylobacter species have developed resistance to existing antibiotics. The development of alternative therapies is, therefore, a necessity. This study evaluates the susceptibility of Campylobacter strains to selected natural products (NPs) and frontline antibiotics. Two C. jejuni…

Community Health Workers and Disease Surveillance in Tanzania: Promoting the Use of Mobile Technologies in Detecting and Reporting Health Events

yunus.karsan@sacids.org
Authors:  Calvin Sindato, Leonard E. G. Mboera, Eric Beda, Mpoki Mwabukusi, and Esron D. Karimuribo Abstract This cross-sectional study was conducted in the Kilosa, Morogoro Urban, Ngorongoro, and Ulanga districts of Tanzania to investigate the practices of community health workers (CHWs) related to disease surveillance functions and to establish their needs and technology capacities. We also established the…

Seroprevalence and associated risk factors of Dengue fever in Kassala state, eastern Sudan

yunus.karsan@sacids.org
Arwa Elaagip, Khider Alsedig, Omnia Altahir, Tellal Ageep, Ayman Ahmed, Hanaa Adli Siam, Abdallah M. Samy, Waleed Mohamed, Fatima Khalid, Suhaib Gumaa, Linzy Elton, Alimuddin Zumla, Najmul Haider, Richard Kock, Muzamil Mahdi, Abdel Hamid   Abstract Dengue is a rapidly growing public health threat in Kassala state, eastern Sudan. The objective of this study was to determine the seroprevalence, entomological transmission indices, and socioeconomic risk factors associated with dengue…

Knowledge, attitudes and practices regarding antimicrobial use and resistance among communities of Ilala, Kilosa and Kibaha districts of Tanzania

yunus.karsan@sacids.org
Gasto Frumence, Sharadhuli Kimera, Taane G. Clark, Helena Legido‑Quigley, Stephen E. Mshana Abstract Background: Antimicrobial resistance (AMR) represents one of the biggest threats to health globally. This crosssectional study determined knowledge, attitudes and practices (KAP) regarding antimicrobial use (AMU) and AMR among communities of Ilala, Kilosa and Kibaha in Tanzania. Method: A semi-structured questionnaire was used to…

Persistent domestic circulation of African swine fever virus in Tanzania, 2015–2017

yunus.karsan@sacids.org
Authors: Clara M. Yona, Merijn Vanhee, Edgar Simulundu, Mariam Makange, Hans J. Nauwynck & Gerald Misinzo Abstract Background African swine fever (ASF) is a highly fatal viral hemorrhagic disease of domestic pigs that threatens livelihoods and food security. In Africa, ASF virus (ASFV) circulates in sylvatic (transmission between warthogs and soft argasid ticks) and domestic (transmission between domestic pigs) cycles, with…

Antimicrobial use and resistance in food-producing animals and the environment: an African perspective

yunus.karsan@sacids.org
Zuhura I. Kimera, Stephen E. Mshana, Mark M. Rweyemamu, Leonard E. G. Mboera & Mecky I. N. Matee  Abstract Background The overuse of antimicrobials in food animals and the subsequent contamination of the environment have been associated with development and spread of antimicrobial resistance. This review presents information on antimicrobial use, resistance and status of surveillance systems in food animals…

Seroprevalence of human Brucellosis and associated risk factors among high risk occupations in Mbeya Region of Tanzania

yunus.karsan@sacids.org
Abstract Background Brucellosis is an infectious zoonotic disease that affects humans, livestock and wildlife. Methods A cross-sectional study was conducted in Mbeya region between November 2015 and January 2016 to investigate the seroprevalence of human brucellosis and identify associated risk factors among individuals in risky occupations in Mbeya Region. A total of 425 humans from six occupational…

Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic Review

yunus.karsan@sacids.org
Noel Gahamanyi, Leonard E. G. Mboera, Mecky I. Matee, Dieudonné Mutangana, and Erick V. G. Komba Abstract Thermophilic Campylobacter species are clinically important aetiologies of gastroenteritis in humans throughout the world. The colonization of different animal reservoirs by Campylobacter poses an important risk for humans through shedding of the pathogen in livestock waste and contamination of water sources, environment, and food. A review of…

Association of brucellosis to abortions in humans and domestic ruminants in Kagera ecosystem, Tanzania

yunus.karsan@sacids.org
Ntirandekura, J-B, Matemba, L.E.; Kimera, S.I.; Muma, J.B. and Karimuribo, E.D.  Abstract Brucellosis is a worldwide zoonotic disease of socio‐economic importance. Understanding the association of this disease with pregnancy outcome has the potential of contributing to the reduction of its reproductive burden in humans and animals among pastoral communities in Tanzania. A prospective cohort study…
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