Our One Health training focuses on developing competence for the application of molecular biology and analytical epidemiology to understand and manage risk associated with infectious diseases through a tiered postgraduate programme.

We aim to develop  world-class research students and fellows, addressing capacity gaps and the convergent need in science and technology that make linking medical and veterinary research efficient and effective in the resource poor settings of sub Saharan  Africa

Seroprevalence and associated risk factors of chikungunya, dengue, and Zika in eight districts in Tanzania

yunus.karsan@sacids.org
Authors: Gaspary O.Mwanyika, CalvinSindato, SimaRugarabamu, Susan F.Rumisha, Esron D.Karimuribo, GeraldMisinzo, Mark M.Rweyemamu, Muzamil M.Abdel Hamid, Najmul Haider, FrancescoVairo, Richard Kock, Leonard E.G.Mboera   Abstract Background: This study was conducted to determine the seroprevalence and risk factors of chikungunya (CHIKV), dengue (DENV), and Zika (ZIKV) viruses in Tanzania. Methods: The study covered the districts of Buhigwe, Kalambo, Kilindi, Kinondoni, Kondoa, Kyela, Mvomero, and Ukerewe in Tanzania. Blood samples were collected…

Development of Nanobodies Targeting Peste des Petits Ruminants Virus: The Prospect in Disease Diagnosis and Therapy

yunus.karsan@sacids.org
Authors: Edson Kinimi, Serge Muyldermans, Cécile Vincke, Steven Odongo, Richard Kock, Satya Parida, Mana Mahapatra and Gerald Misinzo Abstract Peste des petits ruminants virus (PPRV) causes a highly devastating disease, peste des petits ruminants (PPR) of sheep and goats, that threatens food security, small ruminant production, and the conservation of wild small ruminants in many developing countries, especially in Africa. Robust serological and…

Exposure to Salinity and Light Spectra Regulates Glucosinolates, Phenolics, and Antioxidant Capacity of Brassica carinata L. Microgreens

yunus.karsan@sacids.org
Authours:  Sylvia Maina, Da Hye Ryu, Jwa Yeong Cho, Da Seul Jung, Jai-Eok Park, Chu Won Nho, Gaymary Bakari, Gerald Misinzo, Je Hyeong Jung, Seung-Hoon Yang and Ho-Youn Kim Abstract The effect of salt treatment on Brassica carinata (BC) microgreens grown under different light wavelengths on glucosinolates (GLs) and phenolic compounds were evaluated. Quantifiable GLs were identified using ultra-high performance-quadrupole time of flight mass spectrometry.…

Genetic Analysis of African Swine Fever Virus From the 2018 Outbreak in South-Eastern Burundi

yunus.karsan@sacids.org
Authors: Jean N. Hakizimana, Lionel Nyabongo, Jean B. Ntirandekura, Clara Yona, Désiré Ntakirutimana, Olivier Kamana, Hans Nauwynck and Gerald Misinzo Abstract African swine fever (ASF) is a contagious viral disease that causes high mortality, approaching 100%, in domestic pigs and wild boars. The disease has neither a cure nor a vaccine, and it is caused by an ASF virus (ASFV), the only member of…

An assessment of the epidemiology and socio-economic impact of the 2019 African swine fever outbreak in Ngara district, western Tanzania

yunus.karsan@sacids.org
Authors: CC. Kivumbi, C.Yona, J.N. Hakizimana, G.Misinzo Abstract African swine fever (ASF) is a contagious viral transboundary animal disease affecting domestic pigs caused by ASF virus (ASFV). This study was conducted in order to determine the genetic characteristics, risk factors and socio-economic impact of an ASF outbreak in 2019 in Ngara, western Tanzania. Tissue samples from dead domestic pigs with clinical…

Complete genome analysis of African swine fever virus responsible for outbreaks in domestic pigs in 2018 in Burundi and 2019 in Malawi

yunus.karsan@sacids.org
AUTHORS: Jean N. Hakizimana, Jean B. Ntirandekura, Clara Yona, Lionel Nyabongo, Gladson Kamwendo, Julius L. C. Chulu, Désiré Ntakirutimana, Olivier Kamana, Hans Nauwynck & Gerald Misinzo    Abstract Several African swine fever (ASF) outbreaks in domestic pigs have been reported in Burundi and Malawi and whole-genome sequences of circulating outbreak viruses in these countries are limited. In the present study, complete genome sequences of ASF…

Years of potential life lost and productivity costs due to premature mortality from six priority diseases in Tanzania

yunus.karsan@sacids.org
Authors: Susan F. Rumisha, Janeth George, Veneranda M. Bwana, Leonard E. G. Mboera  Abstract Background Mortality statistics are traditionally used to quantify the burden of disease and to determine the relative importance of the various causes of death. Some of the most frequently used indices to quantify the burden of disease are the years of potential life lost (YPLL)…

Review of Peste des Petits Ruminants Occurrence and Spread in Tanzania

yunus.karsan@sacids.org
Erick Komba, Misago Dimson Seth,Richard Kock and Bryony Anne Jones Abstract Peste des petits ruminants (PPR) is an important transboundary animal disease of domestic small ruminants, camels, and wild artiodactyls. The disease has significant socio-economic impact on communities that depend on livestock for their livelihood and is a threat to endangered susceptible wild species. The aim of…

Multidrug-Resistant, Including Extended-Spectrum Beta Lactamase-Producing and Quinolone-Resistant, Escherichia coli Isolated from Poultry and Domestic Pigs in Dar es Salaam, Tanzania

yunus.karsan@sacids.org
Authors: Zuhura I. Kimera, Fauster X. Mgaya, Gerald Misinzo, Stephen E. Mshana, Nyambura Moremi, Mecky I. N. Matee   Abstract We determined the phenotypic profile of multidrug-resistant (MDR) Escherichia coli isolated from 698 samples (390 and 308 from poultry and domestic pigs, respectively). In total, 562 Enterobacteria were isolated. About 80.5% of the isolates were E. coli. Occurrence of E. coli was significantly…

Circulation of dengue serotype 1 viruses during the 2019 outbreak in Dar es Salaam, Tanzania

yunus.karsan@sacids.org
Authors: Gaspary O Mwanyika, Leonard E G Mboera, Sima Rugarabamu, Mariam Makange, Calvin Sindato, Julius J Lutwama, Janusz T Paweska, Gerald Misinzo   Abstract Dengue is an important mosquito-borne viral disease in humans in tropical and subtropical countries. In 2019, a total of 6917 dengue cases were reported in Tanzania based on serological analysis. The aim of this study was to confirm the…
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